Antimalarials are not necessary for every trip, but when they are recommended, understanding why can help you make sense of the advice and address your concerns to keep you safe on your gap year.
Editor’s Note: This is general travel health advice and is not intended to replace individual advice from your GP, specialist nurse or another qualified travel health professional, that has been tailored to your past medical history, medication or travel plans. This article was reviewed and updated on November 2026. It is routinely reviewed every 3 years unless new clinical evidence emerges.
So you have planned your big gap year itinerary, you know roughly where you want to go and what you want to see and do. You are as ready and as excited as you can be to start your big adventure. But there is a problem. Malaria. You have been advised that parts of your route warrant antimalarials. But are they really necessary?
I get it. Nobody wants to go on a gap year and spend all their time worrying about medication, especially tablets that cost a large chunk of your travel budget and come with a long list of potentially serious side effects. Do you really need them? Is the risk really that high? When you are otherwise healthy, it is understandable to question whether taking them is worthwhile.
During more than a decade running my online travel clinic, I heard all those concerns, fears and more. โWill these tablets make me ill when Iโm supposed to be enjoying myself?โ โAre the stories about Lariamโs side effects true?โ โWill they really make me hallucinate or give me depression?โ Those fears, combined with the prospect of remembering a daily or weekly dose when all you want to do is explore the world, often led to one of the most common questions I was asked: โCouldnโt I just be really careful about not getting bitten?โ
As a former nurse with a background in emergency nursing and travel and tropical medicine, I understand and support the clinical reasoning behind those recommendations. But as a backpacker with more than 25 years of travel and over 150 countries behind me, I also understand the reasons that make many travellers question whether antimalarials are worth it.
Iโm not going to dismiss those concerns with โjust take themโ or leave you with a vague instruction to โsee a professionalโ. The guidance is an important starting point, but you deserve to understand why it applies to your trip and how to make the recommended protection work for you.
You deserve to understand when medication offers worthwhile protection, when it is absolutely worth taking, when it is unnecessary and what can be done about the things making you reluctant to take it. A useful recommendation should come with an explanation and a workable plan, one that takes your concerns seriously while helping you get on with enjoying the trip.
What Are Antimalarials?
Antimalarials are medicines used to prevent or treat malaria, a potentially life-threatening infection caused by parasites transmitted through infected mosquito bites. For travellers, โmalaria tabletsโ usually means medication taken before, during and for a prescribed period after visiting a risk area to help prevent the illness. They work against the parasites, rather than stopping mosquitoes from biting, and should be used alongside bite prevention because no antimalarial provides complete protection.
Should You Take Antimalarials On Your Gap Year?
If antimalarials are recommended for any part of your itinerary and a suitable medicine has been identified for you, then yes, you should take that recommendation seriously and take them alongside mosquito bite precautions. Malaria can make you seriously ill and become life-threatening very quickly if left untreated, even if you are otherwise fit and healthy. The right medication, taken correctly, helps protect you from developing the illness and could save your life if an infected mosquito does bite you.
That does not mean, however, that you need malaria tablets for every trip, every country, or even in all parts of countries where malaria is a risk. Recommendations are far more nuanced than that.
Current UK guidance distinguishes between different levels of malaria risk. In high-risk areas, antimalarials are strongly recommended alongside bite prevention: this is where you should plan on taking suitable medication. In low-risk areas, bite prevention and awareness are usually the recommended precautions, although tablets may be appropriate in particular circumstances, such as an increased risk of severe illness. In very-low-risk areas, tablets are generally not advised. Where there is no malaria risk, you do not need medication to prevent it, although avoiding bites still helps protect against other infections.
Those recommendations can change within a country and sometimes with the season. You might therefore need antimalarials for one stretch of your gap year but not another, need them for your whole trip, or follow an entire route where bite prevention alone is the appropriate advice.
Where they are recommended, though, my advice is to take that protection seriously. I understand why the cost or the prospect of side effects might make you hesitate. Those concerns deserve practical answers, so you can find a manageable way to protect yourself rather than feel you have to choose between taking tablets you are unhappy about and going without recommended protection. Understanding why the medication is needed and what suitable options are available makes it much easier to see it as a useful part of preparing for your adventure, rather than an unwelcome inconvenience and expense you are taking on trust.
What Determines Whether You Need Antimalarials?
A conversation with your GP, a specialist travel health nurse or a pharmacist offering travel health consultations should cover your past medical history, any medicines you take, allergies and previous experiences with antimalarials, alongside your destinations, travel dates, length of stay, accommodation and planned activities. Together, these give a picture of both your potential exposure to malaria and which medicines would be suitable for you.
The result should be a thorough, individual recommendation that explains whether you need antimalarials, which parts of your trip require them and what your suitable options are. You do not need every detail booked before that conversation, but sharing your rough route and any likely detours helps make the advice relevant to how you actually intend to travel.
Where You Will Actually Be Exposed To Malaria
One of the first things you will do during a travel health consultation is look at a current malaria map with your planned route in mind. It makes the advice much more tangible: you can see which parts of the journey need particular precautions, rather than being told that a country โhas malariaโ and wondering what that means for your trip.
Malaria is not distributed evenly across every country where it occurs. A relatively small area may have a high risk, while much of the same country has a low or very low risk, or no malaria transmission. Sometimes the difference follows a border region, a particular province or an altitude boundary. In other destinations, risk is widespread. That is why the places you will actually visit matter more than the country name stamped in your passport.
Country malaria maps help show those differences, usually through shaded areas accompanied by a key explaining the recommended precautions. Read that key rather than assuming a particular colour always means the same thing. Also read the accompanying country advice: it may specify seasonal recommendations, exceptions for particular places or circumstances in which some travellers need additional protection. A map showing where malaria occurs is not necessarily a map showing where UK travellers are advised to take tablets.
For a backpacker, the practical task is to follow the whole journey across that information. Locate your main stops, but include the countryside around them, national parks, trekking routes and places where you will break an overland journey. A city marked as having no malaria risk does not tell you the risk of a jungle trek sold by an agency in that city. You need to know where the trek actually goes. Equally, a country containing a high-risk area does not mean that an itinerary hundreds of miles away automatically requires medication.
If you are travelling through several countries, a regional map can help you understand the broad pattern and see how your route connects. However, it is an overview, not enough on its own to decide on medication. The useful next step is to check each countryโs detailed recommendations and map, where available, following your journey across borders. Malaria transmission does not neatly stop at passport control, but neither should advice for one country be assumed to apply unchanged to its neighbour. Your adviser can use those country details to identify which stretches require tablets and how they fit into one continuous travel plan.
The information also needs to be current. Malaria transmission can change as control programmes reduce it, outbreaks occur or environmental conditions alter. Recommendations may be revised as new evidence becomes available, and some areas have different advice at different times of year.
Your destination influences which antimalarial is appropriate as well as whether you need one. Malaria parasites have developed resistance to particular medicines in some parts of the world, so a tablet recommended for one destination may be unsuitable for another. This is resistance in the parasite, rather than your body becoming resistant to the medicine. The country recommendations identify the preventive options expected to work there; your medical history and circumstances then help narrow those down to a suitable choice.
For a journey covering several risk areas, the aim is to find a suitable medicine that covers them all where possible, rather than assume you need a different tablet at every border. Understanding that geographical picture gives you something useful: a clear account of where protection is needed, which medicines can provide it and which parts of your adventure do not require antimalarials.
Whether Medication Offers A Worthwhile Benefit
When assessing whether antimalarials are worthwhile, a travel health professional is weighing two things: the chance of encountering malaria on your likely journey, and the consequences if you become infected. The disadvantages and suitability of medication form the other side of that assessment. The aim is to recommend protection that offers a meaningful benefit for you, rather than prescribe tablets for every conceivable risk.
That conversation needs to reflect how you actually intend to travel. If your route stays wholly within areas where bite prevention and awareness are the recommended precautions, there may be no reason to take antimalarials. But perhaps you are also considering a safari, a rural volunteering placement or an overland detour that would take you into an area where tablets are recommended. Even if that excursion occupies only a small part of your trip, it needs to be included in the assessment.
If that excursion takes you somewhere remote, the assessment also needs to consider how quickly you could reach reliable testing and treatment. Getting away from the usual tourist trail is often half the attraction of backpacking, and preparing for that should help you enjoy the experience. Difficulty obtaining prompt care can make the consequences of infection more serious and influence the prevention plan, even though it does not change the areaโs malaria transmission category. In particular circumstances, additional prescribed emergency treatment may be appropriate.
You do not have to commit to every activity before leaving home. What helps is distinguishing a realistic possibility from somewhere you have no intention of visiting. If a particular detour appeals to you, explain that during your appointment. You can then establish whether your existing protection would cover it or what you would need to arrange before going. That preserves your freedom to change plans without leaving an important decision until you are boarding the bus.
The timing of those plans matters too. Some areas have significant seasonal differences in malaria transmission, so the same journey may warrant different precautions at different times of year. You might visit an area during its low-risk season, travel through a few neighbouring countries and return when the recommendation has changed. Spending longer in an area also creates more opportunities for exposure, although a brief visit does not automatically make recommended medication unnecessary. Your clinician should consider your expected dates and length of stay against the destinationโs current guidance, rather than assume that โdry seasonโ means no risk.
In South Africaโs Kruger National Park, for example, current UK advice recommends antimalarials during the SeptemberโMay transmission season, whereas JuneโAugust is considered very low risk, with bite prevention and awareness recommended. Your travel dates therefore make a practical difference to the advice. Where you stay and whether your visit extends into the evening or overnight also help establish your exposure, but must be considered alongside the recommendation for that season.
Having established what that journey is likely to involve, the clinician also needs to consider what infection could mean for you personally. Pregnancy, a weakened immune system, an absent or poorly functioning spleen and certain other health circumstances can increase the danger from malaria and change the advice. Pregnancy, for example, warrants a discussion about avoiding travel to areas where malaria occurs, rather than simply choosing a tablet. For some travellers, medication may also be considered in low-risk areas where it would not routinely be recommended for others.
Once those factors have been considered, the recommendation should be clear. Where antimalarials are advised, choosing not to take them means giving up a layer of protection considered worthwhile for that journey; being fit and healthy does not provide an alternative defence against the infection. Equally, where tablets are not routinely advised, recommending bite prevention and awareness is a considered clinical decision. It recognises that the additional benefit of medication does not usually justify taking it for that level of exposure.
There really isnโt a one-size-fits-all approach. You should come away understanding whether your likely exposure justifies tablets, how strongly they are advised and whether your health or access to care calls for additional precautions. That gives you a sound basis for preparing for your own adventure, without treating every backpacking trip as though it carries the same risk.
Which Protection Is Suitable For You
If the assessment establishes that your trip warrants antimalarials, your past medical history helps determine which medicine is right for youโor whether any of the usual options would be appropriate. A recommendation to protect yourself against malaria is not a recommendation to take a particular tablet regardless of your health. The aim is to find an effective option whose benefits outweigh its risks for you personally.
That is why the consultation needs to cover your physical and mental health history, including conditions that are well controlled or occurred in the past. Something you no longer consider a problem may still affect prescribing. A previous episode of depression, for example, is relevant when assessing whether mefloquine is suitable, even if you now feel well. Being open about your history helps your clinician avoid an inappropriate medicine; it does not mean you will automatically be unable to take antimalarials or enjoy your trip.
The same care applies to medicines you already take. Your clinician should check for interactions using the names and doses of your prescriptions, medicines bought without a prescription and supplements. Even an apparently ordinary product can matter: some indigestion remedies and mineral supplements can interfere with the absorption of certain antimalarials. Depending on the combination, the solution might involve specific instructions about separating doses or choosing a different medicine. You should not have to work that out yourself from several patient information leaflets.
If you have taken antimalarials before, explaining your experience can help narrow the choice further. There is a difference between an allergy, a serious adverse reaction and nausea that developed when a tablet was taken on an empty stomach. Describe the medicine, what happened and how severe it was, rather than simply saying that antimalarials made you ill. Previous good tolerance is useful information, although it does not replace checking whether the medicine remains suitable for your current health and destination.
Among the options that remain appropriate, there may be room to choose one that fits your trip more comfortably. For example, prolonged, difficult-to-avoid sun exposure deserves consideration when discussing doxycycline, while a diving itinerary needs a careful conversation if mefloquine is being considered. Neither point means that ordinary backpacking activities automatically rule out medication, they just help connect the prescription to what taking it will actually involve.
That practical fit includes whether you can manage the prescribed routine, how soon you enter the risk area and what you can afford. Where several medicines are clinically suitable, those preferences can help guide the choice. Where an option is medically unsuitable, a lower price or more convenient schedule cannot make it appropriate.
Sometimes the available choices are complicated enough to need specialist advice. If no suitable medicine can be identified, the next step is to reconsider how the journey can be undertaken safely, which may include changing the route or avoiding a particular risk area. The need for protection does not disappear because prescribing is difficult. What you should receive is a clear explanation of the problem and a practical way forward, rather than being left to choose between taking an unsuitable tablet and travelling without recommended protection.
When Might You Not Need Antimalarials?
A recommendation not to take antimalarials can be reassuring in its own right. If your itinerary and individual assessment do not warrant medication, you do not need to take tablets simply to feel that you have done everything possible. Appropriate prevention means matching the precautions to the risk, which can legitimately mean travelling without antimalarials.
When Your Itinerary Does Not Include Malaria Risk Areas
A country having malaria does not mean you need antimalarials to travel there. The risk may be concentrated in a particular region that your journey never comes close to, while the places you intend to explore have no malaria transmission. In that situation, taking tablets simply because you recognise the countryโs name from a malaria warning would serve no useful purpose.
I have lost count of how many times I have visited Malaysia and Thailand since the late 1990s. On most of those trips, I have not needed antimalarials, despite malaria occurring in parts of both countries. That has allowed me to enjoy those journeys without the expense or inconvenience of unnecessary medication. The important point is that the precautions matched the places I was visiting and the advice applicable at the time.
That is exactly the reassurance an individual assessment should give you. You might be planning several months of travel through a country, but if the entire route stays outside its malaria risk areas, the length of the trip alone does not create a need for tablets. Equally, crossing into an affected area for an excursion can change the advice even if you spend most of your holiday elsewhere.
Knowing that distinction lets you prepare sensibly and then get on with travelling. You can leave unnecessary antimalarials off the packing list without feeling that you are cutting corners. Bite prevention remains useful against other infections, but there is no reason to medicate against malaria simply because it exists somewhere else in the country.
When Bite Prevention And Awareness Are The Recommended Precautions
The more confusing situation is being told that malaria does occur where you are going, but you do not need tablets. After hearing how serious the disease can be, it is reasonable to wonder why anyone would recommend leaving that risk without medication.
The explanation lies in how medicines are prescribed. A riskโbenefit assessment considers what protection a medicine is likely to provide against the potential adverse effects and disadvantages of taking it. Where the chance of malaria is substantial, the benefit of suitable antimalarials strongly favours taking them. As that chance becomes smaller, the additional benefit of medication becomes smaller as well, while its potential to cause side effects remains.
There comes a point where routinely giving travellers medication would introduce risks and burdens that are not justified by the protection they could reasonably expect to gain. That is why UK guidance recommends bite prevention and awareness alone for some places where malaria transmission still occurs. The remaining risk has been considered; it is sufficiently low that tablets are not usually the proportionate response.
This is the same principle that explains why a medicine can be the right choice for one journey and unnecessary for another. A prescription is not automatically better care, and leaving an appointment without tablets does not mean your concerns have been brushed aside. It may mean the assessment has spared you medication whose expected benefit is too small to justify taking it.
You still have a clear plan to follow: prevent bites and obtain prompt medical assessment if you develop a fever or otherwise unexplained illness during or after possible exposure, explaining where you have travelled. For most travellers visiting these areas, that is appropriate preparation. Personal circumstances can alter the recommendation, but where your assessment supports travelling without tablets, you can accept that advice without feeling obliged to take something โjust in caseโ.
What If You Are Worried About Side Effects?
Being advised to take medication when you feel perfectly healthy can feel pointless. Malaria is something you might encounter; the tablets are something you will definitely have to take. Read a leaflet listing nausea, sun sensitivity or psychiatric reactions, and it is understandable to wonder whether you are exchanging a possible illness for a more immediate problem.
Even worse was the possibility of the antimalarials themselves making you even sicker than malaria would, if all the horror stories were to be believed.
That was the concern I heard most often during more than a decade running my online travel clinic. Travellers wanted protection, but they wanted to know what it might cost them beyond the price of the prescription. Would they feel sick on the road? Would their choice of medication interfere with days spent outdoors? Were the frightening stories about Lariam making you hallucinate and go psychotic real? Sometimes the solution seemed far worse than the potential problem. And honestly, I get it.
The truth is like all drugs, antimalarials do have different side-effect profiles, but a possible reaction is not a prediction of what will happen to you. Many travellers take them with mild effects or none at all. The aim is to understand the relevant risks, have an honest conversation about problems and alternatives, choose suitable protection for you and know what to do if it does not agree with you, rather than feel you must either tolerate anything or go without.
Nobody Wants Their Medication To Spoil Their Trip
If you are heading somewhere hot and tropical, hearing that doxycycline can make your skin more sensitive to sunlight immediately raises questions about beaches, boat trips and days spent trekking. The possibility of nausea feels particularly unwelcome when your itinerary already involves winding roads and crowded overnight minibuses. These are not unreasonable concerns. You want protection from malaria, but you understandably want to know whether taking it could interfere with the experiences you are travelling to enjoy.
Even a side effect described as โmildโ can matter when it affects something you have spent months looking forward to. A manageable inconvenience at home might feel rather different halfway through a trek or on an overnight bus. Explaining that malaria is serious does not make those concerns disappear, and you should not feel that accepting protection means accepting that your enjoyment of the trip is unimportant.
The useful question is how well a particular medicine fits what you intend to do. If sun sensitivity worries you, explain the activities behind that concern. A few afternoons on a beach and a week-long trek with little shade present different practical considerations. Your clinician can explain what precautions would involve and whether another suitable medicine would be a better fit.
UK guidance specifically recognises sun exposure when advising on doxycycline and diving when considering mefloquine for example. This is why mentioning activities you are seriously considering, even if they are not booked, is really important. This way clinicians can tailor your prescription to you. You are not being difficult by asking how medication will affect your adventure; you are helping your clinician choose protection you can use safely while enjoying it.
A Listed Side Effect Does Not Mean You Will Experience It
All medicines can cause side effects, including familiar ones you might take without much thought. Antimalarials are no different, but reading a long list of possible reactions can make taking them sound far more daunting than it usually is. If this is you, you really aren’t alone. Almost everyone looks at the side effects listed for antimalarials and instantly gets put off. The important thing to remember is that there is a huge difference between something that can happen and something you should expect to happen, and the fact is many travellers take antimalarials with very mild side effects or none at all.
Medicine leaflets list every recognised adverse effect so you can understand the risks and know when to get help. They really aren’t there to put people off or scare them. Serious reactions need to be included even when they are exceptionally uncommon. That’s the whole basis of informed consent. But being warned about a side effect does not mean it is likely to happen to you.
Take paracetamol as an extreme example. Its recognised potential adverse effects include toxic epidermal necrolysis, a very rare, serious reaction that causes skin to blister and peel and reveal necrotic, dead looking tissue. That sounds horrifying, yet most of us would take paracetamol for a headache without much hesitation or though. Familiarity helps us keep that possibility in perspective. An unfamiliar antimalarial, accompanied by a few alarming travel stories, can be much harder to view in the same measured way.
The point is not that every medicine carries the same risks. It is that a medicine having potentially serious side effects does not, by itself, tell you whether taking it is a sensible choice. I have fortunately never experienced side effects from antimalarials myself, while other people have genuine difficulties with a particular medicine. Both experiences belong in an honest discussion.
Your clinicianโs job is to put those possibilities into context: to weigh the expected protection against the potential harms, identify reasons a particular medicine might be unsuitable and explain the effects that require attention. That allows you to understand the prescription without either dismissing the warnings or assuming the worst will happen.
If you do find that a medicine does not agree with you, that experience can guide a change of plan. Different antimalarials have different side-effect profiles, and an alternative may suit you better. Starting recommended protection does not mean agreeing to endure whatever happens for the rest of your trip.
Understanding The Concerns About Lariam And Mefloquine
Sun sensitivity or nausea can be unpleasant enough, but hearing stories of frightening hallucinations or severe psychiatric reactions raises a different level of concern. For many backpackers, Lariam is the name behind their fear of antimalarials in general, particularly when disturbing accounts are attributed to the whole group of medicines rather than one specific drug.
Those concerns have a genuine medical basis. Mefloquine, the medicine sold under that brand name, can cause psychiatric and neurological side effects, including depression, anxiety, hallucinations and problems with balance. Some reactions can be serious or persist after the medicine is stopped. The US Food and Drug Administration introduced a boxed warning about neuropsychiatric reactions, including neurological effects that may persist or become permanent. In the UK, the MHRA has strengthened warnings and introduced measures intended to reduce these risks.
That, quite understandably, causes many travellers to nope out of the idea of taking it very quickly. It deserves an honest explanation, rather than well-meaning but inadequate reassurance that the stories are exaggerated.
The possibility of serious reactions is precisely why mefloquine should never be prescribed without careful consideration of your medical history. Current UK guidance rules it out for malaria prevention in people with a current or previous history of depression and certain other psychiatric conditions, or a history of seizures. Your clinician should actively ask about these matters, including problems that happened years ago and no longer affect your daily life. They may ask about epilepsy or serious mental health disorders in first-degree relatives, because that information can influence the assessment, although a condition in a relative does not automatically rule the medicine out.
These questions provide a practical safeguard: they help identify people for whom another medicine would be more appropriate before the first dose is taken. Screening cannot predict every reaction, but it can identify known reasons to avoid mefloquine. That is why giving an accurate medical history matters far more than trying to decide whether your experience will resemble a frightening account you have read online.
Mefloquine remains an effective option that most travellers who take it tolerate. Its recognised risks do not make every prescription inappropriate, but its usefulness does not justify overlooking a history that makes it unsuitable. If it is being recommended, you should understand why it fits your circumstances and have the opportunity to discuss any concerns that remain after the assessment.
That conversation should include knowing what changes require action. Nightmares or abnormal dreams, difficulty sleeping, acute anxiety, depression, restlessness, confusion or other changes in your mental state can be warning signs of a more serious reaction. Stop taking mefloquine immediately and obtain medical advice if any of these develop. Donโt wait, donโt take any more doses, and donโt assume you need to push through the symptoms to remain protected. A clinician can assess what is happening and arrange suitable alternative malaria prevention. Symptoms can persist after stopping, so obtaining help remains important.
The reassurance comes from having those safeguards and options, rather than pretending the risk does not exist. If your history makes mefloquine unsuitable, or you develop a reaction, another antimalarial may provide the protection you need without the same concerns. Side effects are a serious consideration, and it is understandable that they can put you off. They can, however, be addressed through appropriate prescribing, prompt assessment and a change of medicine where necessary. Where malaria protection is recommended, the aim is to resolve the problem while maintaining that protection, rather than leave yourself exposed because one option worries you or does not suit you.
Make A Plan In Case Your Medication Does Not Suit You
One of the most reassuring things you can do before starting antimalarials is establish what will happen if they do not agree with you. You are not committing yourself to taking an unsuitable medicine for months, but knowing that alternatives exist is only useful if you can obtain advice and arrange a change. A little preparation gives you a way to deal with problems without abandoning protection or allowing them to dominate your trip.
Start with the prescribed starting date and look at where you will be. Mefloquine is normally started two to three weeks before entering a malaria risk area, allowing time to assess tolerability. Doxycycline and atovaquone/proguanil usually start one to two days beforehand. That shorter lead-in can be convenient, particularly for last-minute plans, but it leaves less time to recognise an early problem and arrange an alternative before exposure.
For me, this is often where UK guidance falls a little short of the practical reassurance travellers need. Having enough time for medication to provide protection is not the same as having comfortable breathing space to resolve a problem with it. The recommended schedules are important, but following them can still leave you worrying about what happens if you feel unwell just before a flight, border crossing or remote excursion. Fortunately, you can plan around that difficulty.
Raise the concern when your medication is prescribed. Ask how the starting schedule fits your journey and how you can obtain a review if problems develop. If you will be at home, establish how to contact the prescribing clinic and how quickly they could help. A review before departure may be useful, but avoid making an appointment the day before your flight your only opportunity to resolve a problem. Contact the clinic as soon as symptoms arise so there is more time to assess them and arrange a replacement if necessary.
If you will already be travelling, you can apply the same approach by spending a few days in a city or major travel hub with access to a reputable clinic when your course begins, before heading into the malaria risk area. Identify somewhere suitable in advance and leave enough flexibility to stay longer if you need help. Those days can still be spent enjoying the destination; the practical advantage is being able to reach a clinician rather than starting your tablets as you disappear somewhere remote. Follow the starting schedule agreed with your prescriber rather than creating your own trial course.
With support arranged, the next step is to make taking the medicine as straightforward as possible. Understanding the administration instructions gives you some control over avoiding problems that are preventable. Doxycycline, for example, should be swallowed with plenty of water, and you should remain upright for at least an hour afterwards to reduce irritation of the oesophagus. Atovaquone/proguanil should be taken with food or a milky drink to help absorption.
Honestly, these instructions can be surprisingly easy to forget. I have lost count of the travellers who have told me they missed their atovaquone/proguanil with dinner and simply took it before bed without eating. The timing felt like the important thing, so the instruction about food slipped their mind.
I personally find breakfast the easiest routine to build it around. Get up, get ready, have something to eat and take the medication as prescribed. It gives the dose a familiar place in the day, even when the destination keeps changing. Your pharmacist can help you find a routine that fits your prescription and how you travel.
If symptoms develop later, donโt hesitate to use the support you have arranged and get medical advice. Explain which medicine you are taking, when you started and what has happened. Some difficulties may be manageable with advice about administration; others require a different medicine or urgent assessment. The mefloquine warning symptoms described above require stopping it and obtaining help immediately, rather than waiting for a routine review.
Where a replacement is needed, obtain clear instructions about stopping the original medicine, starting the alternative and completing the course. Different antimalarials cannot simply be exchanged tablet for tablet, but a clinician can plan the change to maintain protection. A few symptom-free days cannot rule out every later reaction, so keep the medicine details and instructions accessible throughout your trip.
Side effects are a serious concern, and it is understandable that they can put people off taking antimalarials. But where protection is recommended, the answer is to address those concerns rather than leave yourself exposed to malaria. Having a plan gives you something more useful than hoping for the best. You know how to take the medicine, where to obtain help and how an alternative can be considered if needed, giving you a way forward that protects both your health and the adventure you want to enjoy.
What If You Canโt Afford Antimalarials For Your Whole Trip?
Antimalarials can be expensive, especially if you need to take them for long periods, and it really is not unreasonable to question that. Depending on the medicine and how long you need it, you could be looking at a bill running into hundreds of pounds or moree. When you have worked hard to save for your trip and are trying to make every penny last, questioning that expense is entirely reasonable.
I get it. You look at the price and immediately start working out what that money could buy instead. Another few weeks in a beach hut on a Thai island, that trek in Peru you have been looking forward to, or simply a little more time on the road before you have to come home. I have made exactly those calculations myself. Being told โyou canโt put a price on your healthโ is not particularly helpful when your bank balance says otherwise.
Personally, I put necessary medication in the same category as my flights and travel insurance. Together, they are the cost of getting out there. Where antimalarials are recommended, I take the โjust in caseโ approach and budget for them from the start, even if I would much rather spend that money on something more exciting.
But that does not mean you have to accept an unaffordable bill without questioning your options. If the cost is putting protection out of reach, say so. There may be a suitable cheaper medicine, you may only need tablets for part of your journey, or a change of route could let you enjoy the experience you wanted without the same expense. Those are possibilities worth working through before deciding that you simply cannot afford to protect yourself.
Could A Different Route Give You The Experience You Want?
Before deciding that antimalarials are going to swallow an unaffordable chunk of your budget, it is worth looking at which part of your route creates the need for them. You may be spending most of your trip somewhere tablets are unnecessary, with one excursion taking you into an area where they are recommended. If you could enjoy a similar experience elsewhere, a change of plans might save you that expense without feeling like you have sacrificed part of your adventure.
If you are planning a safari in South Africa between September and May, for example, a visit to Kruger would normally mean budgeting for antimalarials. But if what you really want is to see elephants, spot the Big Five and enjoy a few days of wildlife watching, you could head to Addo Elephant National Park in the malaria-free Eastern Cape instead. You still get the safari experience, with no need for malaria tablets for that part of your journey. If Kruger itself is somewhere you have always wanted to visit, going between June and August may be another option: current UK guidance considers the risk very low during those months and recommends bite prevention and awareness rather than routine antimalarials.
That gives you something useful to explore during your travel health appointment. Bring your rough itinerary and explain which experiences you are particularly keen on, so you can identify whether an alternative would change the medication recommendation. You can then weigh that option against the rest of your plans, including what it would cost to get there. There is little financial benefit in saving on tablets if reaching a different destination adds considerably more to your transport and accommodation bill.
Of course, if a particular place is the reason you are travelling, changing it may hold no appeal whatsoever. You do not have to give up a dream destination to avoid taking medication. But where your plans are flexible, choosing a different park, excursion or time of year can be a sensible way to keep the experience while reducing the cost of preparing for it. Just make sure the recommendation covers your revised route as a whole, because changing one stop will not remove the need for antimalarials if another part of the journey still warrants them.
Match The Course To The Time You Actually Need Protection
A six-month trip does not necessarily mean paying for six months of antimalarials either. If only a few weeks of your route take you through areas where tablets are recommended, your prescription can be planned around that part of the journey. You still need the full course, including the required doses before entering and after leaving the risk area, but there is no benefit in buying months of additional medication for destinations where you do not need it.
This is where putting your route and approximate dates in front of your prescriber can make a substantial difference to the bill. You might spend the first two months somewhere medication is unnecessary, visit a risk area for three weeks, then continue travelling elsewhere. Your starting date should relate to entering that area, rather than automatically to the day you leave the UK, and your finishing date should follow the prescribed period after your last exposure.
That period afterwards is part of the protection, even if you are now enjoying a beach somewhere with no malaria risk. Leaving the area prevents further exposure there; it does not remove parasites that may already have entered your body. Different medicines act at different stages of the parasiteโs development, which is why some courses continue for seven days after leaving and others for four weeks. Obviously you will still need to take the full dose, but if the rest of your trip is in a low or no risk area, that shorter time period means the end of the course you have to buy.
If your journey moves in and out of risk areas, ask your clinician to work through those visits together. A week somewhere without malaria may fall within the course you still need after the previous stop, with another risk area coming up before it finishes. Continuing one course may therefore make more sense than repeatedly stopping and restarting. Having the entry and exit dates written down helps you understand both the supply you need and why apparently risk-free days may still involve taking tablets. In this circumstance you can look at modifying your route so the malaria risk areas can be visited one after the other, then you can visit the low to no risk areas. Obviously this is more practical in one country than it is over several, but you still may be able to change some things to make it easier.
Where your plans are flexible, build that flexibility into the calculation rather than buying the smallest possible supply and hoping the dates work out. Explain where you might stay longer or return later, so you can agree what an extension would mean and how you would obtain additional medication if needed. The saving comes from matching a complete course to your actual exposure, while leaving you enough room to enjoy the freedom of the trip.
Compare The Full Cost Of Suitable Alternatives
If the medicine recommended to you is more than you can comfortably afford, say so before buying it. There may be another option that provides appropriate protection for your destination and suits your medical history at a lower cost. You are not asking for inferior care by raising your budget; you are giving your prescriber the opportunity to find a plan you can afford to follow.
The useful comparison is between medicines that are suitable for you, rather than simply choosing the cheapest tablet available. If an alternative would interact with your regular medication, is inappropriate for your destination or previously caused a significant reaction, a lower price does not make it a bargain. Where several options are appropriate, however, cost can reasonably help you choose between them. Paying more does not automatically buy better protection, just as paying less does not automatically mean you will experience more side effects.
Ask for the price of the complete course for your itinerary. Comparing daily or weekly prices can be misleading because the number of doses differs between medicines. Atovaquone/proguanil continues for seven days after leaving the risk area, while doxycycline continues for four weeks. That difference affects the total bill, particularly for a short visit, so the price per tablet alone cannot tell you which course will cost less.
You may also be able to reduce the price without changing the active medicine. Ask whether a licensed generic version is available instead of a particular brand, and compare the total supplied cost through reputable pharmacies, including any consultation, prescription or delivery charges. Have the medicine, strength and quantity confirmed so you are comparing the same course rather than two prices that cover different amounts of protection.
That gives you a much more useful question than โWhich antimalarial is cheapest?โ: โOf the options that work for my trip and are suitable for me, which complete course can I most comfortably afford?โ You may find a worthwhile saving, or discover why the more expensive option remains the better fit. Either way, you can make the decision knowing what the alternatives actually offer.
Avoid False Economies From Unverified Medication
You can buy medication more cheaply abroad, sometimes considerably so. When you have just been quoted for several months of antimalarials, waiting until you arrive can therefore sound like an obvious saving. But you need to know that you can obtain the right medicine from a reliable source, and that waiting will not leave you without protection when you need it.
If your journey takes you straight into a malaria risk area, your prescribed course needs to start before you get there. Planning to find a pharmacy after landing could mean arriving without the recommended protection already in place. Even if your itinerary gives you time to buy medication before entering the area, you cannot assume that the medicine prescribed at home will be readily available at your destination.
You may encounter unfamiliar brands, different tablet strengths or an entirely different drug offered as an equivalent. A different brand can be perfectly legitimate, but you need someone qualified to confirm the active ingredients, strength and suitability rather than accept a sellerโs assurance that โthese are malaria tabletsโ. Fake or substandard products introduce a more serious problem: you could take every dose exactly as instructed while receiving little or none of the protection you believe you have.
That is why UK guidance recommends obtaining your required supply from a reputable UK source before travelling. Saving a few quid is not worth arriving unprotected or gambling on what is actually in the packet. There are safer ways to reduce the bill, including comparing reputable suppliers and asking about suitable alternatives before departure.
Of course, a long or open-ended trip may mean obtaining a further supply abroad. Plan that around a reputable major clinic or established hospital with a pharmacy in a larger city or tourist hub, where a clinician can review your prescription and arrange reliable medication. Take the original packaging or a record of the generic name, strength and schedule, and allow time to obtain the supply before yours runs out.
There are excellent medical services abroad, and using them when needed is a sensible part of independent travel. The distinction is between obtaining medication through an established service and buying whatever is cheapest from a backstreet shed with a pharmacy sign. The price may be tempting, but confidence in your malaria protection needs to rest on rather more than that.
What About Taking Antimalarials For An Extended Trip?
Taking medication for months on end over a big trip when you are otherwise healthy can feel like a lot to ask. You may be fine with a short course of a couple of weeks or so; you may even accept the possibility of short-term side effects for that length of time. But what if your time in high-risk areas runs on for a few months, or six months, or longer? It is understandable to worry about what prolonged use could do to your body or whether harm could build up unnoticed. Having to remember a daily or weekly tablet for the foreseeable future can make that commitment feel even less appealing.
Being told that a medicine is suitable for your destination does not necessarily settle those worries. You want to know whether taking it for six months is a different proposition from taking it for a fortnight, whether there is a limit to how long you can safely continue and whether you will need any checks along the way. And even if you are reassured about its safety, there is still the prospect of getting thoroughly fed up with taking it.
Long-term malaria prevention is an established part of travel medicine, and UK guidance specifically addresses extended use. There are options for travellers spending months in risk areas; you are not automatically stretching a short-holiday prescription beyond what it can reasonably cover. The useful reassurance comes from understanding the evidence for your particular medicine and having a plan that makes continuing it manageable.
Does Taking Them Long Term Mean Causing Harm?
Taking a medicine for longer does not automatically mean it becomes progressively more harmful. For the antimalarials commonly prescribed to UK travellers, the available evidence supports use over months and, in appropriate circumstances, years. If you need protection for six months, that is a recognised prescribing situation, rather than an unusually long course with no guidance behind it.
Current UK guidance gives specific reassurance about the usual options. It supports doxycycline for at least up to two years, atovaquone/proguanil for travel up to a year, and mefloquine for up to three years when it is tolerated without significant side effects. Longer use may be appropriate where continued exposure justifies it. These periods are not expiry dates after which the medicine suddenly becomes unsafe; they help clinicians judge extended use against the available evidence and your circumstances.
That evidence needs explaining honestly. Much of the reassurance comes from experience of prolonged use without evidence of accumulating harm, rather than trials capable of proving that every possible long-term problem has been excluded. It supports prescribing suitable medication for an extended journey without promising that taking it is entirely risk-free.
If you are tolerating your prescribed medicine, there is generally no benefit in changing it simply because several months have passed. Introducing a different drug can bring a fresh possibility of side effects, while taking breaks during ongoing exposure can interrupt protection. Your body does not routinely need a โrestโ from antimalarials. Any planned stopping or restarting should follow the exposure and prescribed schedule, rather than an arbitrary number of weeks on tablets.
Where review or monitoring is appropriate, arrange it as part of the long-term plan. For prolonged mefloquine use, for example, the product information recommends periodic liver-function checks and eye assessments. Your prescriber should explain what is needed for your medicine and health, and how to organise it while travelling.
The balance also includes what happens if you stop protecting yourself. Months spent in an area where malaria prevention is recommended create continuing opportunities for infection. Feeling settled, knowing your way around and having stayed well so far do not remove that exposure. For an appropriately selected medicine, continuing the course can therefore remain the safer choice, rather than allowing understandable worries about prolonged use to leave you without protection.
Make The Routine Easier To Maintain
Even when you are reassured about long-term safety, you can still get thoroughly fed up with taking tablets. At the start of a trip, medication is part of your carefully organised preparations. A few months later, when you are packing for another early bus or have lost track of which day it is, remembering it can feel like a chore. That does not make you irresponsible; it means the routine needs to work on an ordinary, occasionally chaotic travel day.
The easiest routine is usually one that requires the least conscious effort. Building your dose around a regular meal, as I do with breakfast, gives it a familiar place in the day even when everything around you changes. A phone reminder can provide a backup, particularly for a weekly medicine, and recording the dose when you take it avoids that irritating moment later when you cannot remember whether you actually swallowed it or only thought about doing so. Keep the tablets somewhere accessible while following their storage instructions, rather than buried beneath everything else in your backpack.
A routine can also become harder to maintain because something about the medicine is bothering you. If you keep putting off a dose because it makes you nauseous, or are deliberately skipping tablets because you remain worried about harm, another alarm will not solve the underlying problem. Explain what is happening to a clinician so the difficulty can be addressed. A suitable change of medicine may help, but switching yourself or taking occasional breaks can leave gaps in protection.
If you miss a dose, follow the instructions for your particular medicine or ask a pharmacist how to proceed; do not improvise by doubling up. Keep your prescribed finishing date somewhere obvious as well. Leaving a risk areaโor arriving homeโcan make it feel as though the job is done, when completing the remaining course is still part of protecting yourself.
You do not need to spend months thinking about malaria. A manageable habit lets the medication become a small part of your day, leaving your attention free for the journey. The aim is to make continuing protection easy enough that getting bored with the routine does not become a reason to lose it.
Canโt You Just Be Really Careful About Mosquito Bites?
With concerns about side effects, the expense and the prospect of taking tablets for months, concentrating on mosquito bite prevention can seem like the easiest answer. If malaria is transmitted through mosquito bites, surely avoiding those bites would let you avoid both the illness and the medication? You are already planning to use repellent, cover up and sleep under a net where needed. Why not just be particularly careful?
That reasoning is understandable, and bite prevention genuinely is an essential part of protecting yourself. UK guidance describes it as the first line of defence against malaria, and for some destinations it is the main recommended precaution alongside awareness. The difficulty is turning โI can substantially reduce my chances of being bittenโ into โI can reliably avoid every potentially infectious bite throughout this tripโ.
Antimalarials help protect you if an infected mosquito does get through those precautions. Their recommendation does not mean your efforts to avoid bites are pointless or that you cannot be trusted to use repellent. It recognises that even careful travellers cannot guarantee complete protection from bites, and that the remaining risk can justify another layer of protection.
Bite prevention is important wherever mosquito-borne infections occur, including places where malaria tablets are unnecessary. In high-risk malaria areas, however, bite precautions and suitable antimalarials are intended to work together: one reduces the chance of an infectious bite, while the other helps prevent malaria developing if you are bitten. Neither provides complete protection on its own, and taking tablets is no more a reason to abandon your repellent than using repellent is a reason to leave recommended tablets behind.
Why Being Careful Does Not Eliminate Every Bite
You can use a good repellent, cover exposed skin and sleep under a properly fitted net, and still occasionally get bitten. That does not mean those precautions have failed you or that you have been careless. They reduce exposure considerably, but maintaining an uninterrupted barrier between yourself and every mosquito is difficult in ordinary travel.
Think about a day spent exploring somewhere hot and humid. You apply repellent before heading out, then sweat, swim or shower, changing how long that application protects you. A patch of skin may get missed when you reapply, or a sleeve may ride up while you are sitting outside. By evening, you might be waiting for transport or enjoying dinner somewhere quite different from the screened room where you intend to sleep. Good precautions can fit around all of that, but intending to be diligent is different from being able to promise that nothing will ever get through.
The mosquitoes that transmit malaria mainly bite between dusk and dawn, although biting patterns vary and exposure can occur outside those hours. Sleeping under a net therefore protects you during an important part of the night, but it cannot cover the evening you spend outside it. This is why combining sensible precautions works better than putting all your faith in one product or habit.
None of that means you should spend your adventure monitoring every inch of skin. Most mosquito bites do not transmit malaria, and getting bitten is not a reason to assume you will become ill. It simply explains why โIโll be really carefulโ cannot provide the same reassurance as a prevention plan that accounts for bites occasionally happening.
Why Antimalarials And Bite Prevention Work Together
If an infected mosquito does bite you, an antimalarial is intended to act against the parasites it introduces before they cause malaria. That gives the medication a different job from your repellent, clothing or net. Those precautions help prevent the infectious bite; the medicine provides protection against what can happen afterwards.
In areas where tablets are recommended, that combination allows for the reality of travelling. Your protection does not depend entirely on perfect repellent coverage during every bus journey, meal and nightโs sleep. Taking the prescribed medicine correctly gives you an additional defence when a bite happens despite your efforts.
The same reasoning works in the other direction. Antimalarials do not provide complete protection, so they are no reason to become relaxed about bites. They do not prevent dengue or other mosquito-borne infections either. Keeping up bite precautions protects against more than malaria and reduces the number of opportunities for infection in the first place.
For someone reluctant to take medication, the temptation is to make bite prevention work harder so tablets become unnecessary. But where the assessment recommends both, the residual risk has already been judged sufficient to warrant medication alongside those precautions. The useful response is to resolve concerns about the prescription and find suitable protection, rather than expect repellent alone to replace it.
Why Do Other Travellers Say Antimalarials Are Unnecessary?
Being advised to take antimalarials can become much harder to accept when other travellers insist you do not need them. If several people have visited the same country without taking tablets and stayed perfectly well, it is understandable to wonder whether your recommendation is excessive. Their experience sounds reassuring, particularly when it offers a way around the expense and side effects you were already concerned about.
Sometimes there is a straightforward explanation: they genuinely did not need medication for their particular trips. They may have stayed outside the affected areas, visited during a different season or followed a route where bite prevention and awareness were the recommended precautions. A country name can make two journeys sound identical when the actual exposure was quite different.
But someone can also travel without recommended protection and be fortunate enough not to become infected. Hearing that they stayed well does not distinguish a sensible decision from a gamble that happened to work out. Even several uneventful trips cannot establish that the advice was unnecessary, because a risk does not have to result in illness every time to be worth protecting against.
This is where Dave at the hostel tends to enter the conversation. Dave has been everywhere, knows a brilliant beach bar and assures you that malaria tablets are a scam because he has never taken them. Unfortunately, his ability to locate cheap beer does not make him qualified to assess your prescription. He may be an excellent source of travel tips while talking absolute bollocks about malaria.
The difficult part is that first-hand experience feels persuasive. Someone sitting opposite you, describing the trek you want to do, can seem more relevant than advice received before departure. Their account may help you understand the journey, but it cannot establish which medicine suits your health or whether the current recommendation applies to your dates and route. The same limit applies to your own previous visits: knowing a place well does not provide immunity, and having stayed healthy there before does not guarantee another uneventful trip.
If conflicting accounts leave you doubtful, turn that doubt into a specific question. Explain the comparison to your clinician and ask which part of your itinerary or circumstances accounts for the recommendation. You may discover that the other traveller followed a different route, that the guidance has changed or that something in your own plans warrants additional protection. That gives you an answer you can use, rather than leaving you to choose between two competing assertions.
You do not have to dismiss other backpackersโ experiences to make a sensible decision. Enjoy their stories, borrow their practical tips and investigate anything useful they raise. Just keep their experience in its proper place: Dave staying well is good news for Dave, but it is not a reason to abandon protection recommended for you.
What If Your Route Is Still Flexible?
Part of the pleasure of backpacking is being able to change your mind. You might stay somewhere for an extra fortnight, hear about a trek you had never considered or decide to cross a border instead of catching the flight you originally planned. Having to organise malaria protection can feel at odds with that freedom, especially when you cannot say exactly where you will be in three monthsโ time.
You do not need to turn your gap year into a rigid itinerary to prepare properly. A useful prevention plan can accommodate likely detours and give you clear boundaries: which journeys your existing advice covers, and which changes mean arranging additional protection before you go. That is far more helpful than either taking medication for every hypothetical destination or leaving the decision until you arrive somewhere it is needed.
The aim is to make changing direction manageable. Knowing what needs checking, how much notice your prescribed medicine requires and where you can obtain reliable advice lets you make those decisions while you still have options. You can keep the spontaneity without discovering that tomorrowโs adventure requires preparations you have not made.
Prepare For The Detours You Are Likely To Take
Most backpackers have some idea of their route, even when the dates and details are open. You might know that you want to explore a particular region, that a border crossing appeals to you or that you are likely to add a jungle trek if you find one you like. Bring those possibilities into your initial consultation alongside the places you definitely intend to visit. They give your clinician something realistic to plan around without requiring you to commit to every stop.
Ask them to help you understand what those choices would mean for your protection. If you follow your main route, will bite prevention be sufficient? If you add the excursion, would you need to start medication, extend an existing course or obtain advice about a different medicine? Having those answers can turn a vague instruction to โcheck if your plans changeโ into something you can actually use.
Where an excursion into a risk area is a genuine possibility, your clinician may be able to prescribe a suitable supply in advance, with written instructions explaining when it would be needed and how to take it. That can be particularly useful if obtaining reliable medication along the route would be difficult. It does not mean you must take the tablets regardless of where you go; it means the decision and prescription have been considered before you need them.
Keep those instructions with your medication and save the relevant country information so you can revisit the reasoning. If the detour becomes a firm plan much later, check that the recommendation remains current. You have prepared for an option, rather than given yourself a permanent prescription for any journey that sounds vaguely similar.
Know What Needs Updating Before You Change Plans
When an unexpected opportunity comes along, establish where it will actually take you before committing to leave. A trek departing from the town where you are staying may enter a different risk area, and an overland journey may involve an overnight stop you had not accounted for. Get the route and accommodation details from the operator or work them out from your intended stops, then compare them with the current TravelHealthPro country advice and the plan agreed with your clinician.
If the new journey falls outside that plan, obtain updated advice while you are still somewhere you can act on it. Explain what has changed and which medication, if any, you are already taking. The useful outcome is a clear answer about whether your current protection covers the change, whether you need a further supply or whether a different prescription is necessary.
Do this before buying a non-refundable excursion or boarding transport into the area. A suitable medicine may be available, but you need time to obtain it and follow its prescribed starting schedule. If that cannot be arranged before tomorrowโs departure, staying a little longer in a travel hub or choosing a later excursion is a practical way to preserve the experience without arriving unprepared.
An extension can be easier to overlook than a new destination. You may be perfectly happy where you are and simply decide to stay for another month, but that can affect your supply, the season in which you are exposed and the date you should finish your course. Arrange the additional medication before you run short, and confirm how the revised departure date changes the doses required afterwards.
These checks need not become a major exercise every time you alter a booking. Once you understand what your existing plan covers, many decisions will be straightforward. Where a change does affect your protection, dealing with it before moving on keeps you free to enjoy the detour rather than spend it trying to repair a gap in your preparations.
Leave Your Appointment With A Usable Plan
A prescription alone does not answer every concern that brought you to the appointment. You should leave understanding why the recommendation makes sense for your journey and how to follow it, whether that means taking antimalarials or relying on bite prevention and awareness.
Before you finish, make sure you know:
- Which parts of your route require medication, and which do not.
- Why the chosen medicine suits your health and travel plans.
- The exact dose, how to take it, when to start and when to finish.
- What to do if you miss a dose, vomit after taking it or develop side effects.
- How much medication you need, what the complete course costs and how to arrange a reliable further supply if necessary.
- Which changes of plan require updated advice.
- Where to obtain help if the medicine does not suit you, and when symptoms require urgent attention.
Ask for the important instructions in writing, particularly if your journey involves several separate visits to risk areas. It is much easier to follow a clear schedule than reconstruct a conversation months later while packing for a border crossing.
If something still makes you reluctant to take the medication, say so before leaving. You do not have to pretend that an explanation has settled a concern when it has not. The appointment should give you a plan you understand and can realistically follow, rather than a packet of tablets you remain unsure about taking.
If You Become Unwell During Or After Travel
Taking antimalarials correctly and being careful about bites substantially reduces your risk, but it cannot rule malaria out completely. If you develop a fever, feel hot and shivery or have an otherwise unexplained flu-like illness during or after visiting a malaria risk area, obtain urgent medical assessment. Do not wait to see whether it settles, assume it is a medication side effect or put off getting help because you took every tablet.
While travelling, go to a suitable clinic or hospital where malaria testing can be arranged. Your insurerโs medical assistance service can help identify somewhere appropriate, and accommodation staff or guides may help with transport. Do not delay urgent care while waiting for an insurer to approve it, and do not wait until you get home. If you are already back in the UK, request an urgent GP appointment or contact NHS 111, explaining the possible malaria exposure.
Tell the clinician where you travelled, when you were there and which antimalarial you took. Include earlier stops: becoming ill somewhere without malaria does not exclude an infection acquired elsewhere. Symptoms can begin months after exposure, so mention travel to risk areas during the previous year, and any older exposure if relevant.
Malaria cannot be reliably identified or excluded from symptoms alone. Blood testing is needed, and an initial negative result may need repeating if suspicion remains. If you continue to feel unwell or deteriorate after an assessment, seek help again and repeat your travel history. Confusion, seizures, breathing difficulty or collapse require emergency care immediately.
This is a reason to act promptly if illness occurs, rather than spend your trip expecting it. Malaria is treatable, and recognising the need for assessment gives you the best opportunity to receive the right care quickly.
Get Prepared, Then Get On With Enjoying Your Trip
You have every right to question whether you need antimalarials. Asking about side effects, cost or months of medication is part of making an informed decision, and you deserve answers that help you do that. Hopefully, understanding how the recommendation is made makes it easier to see where tablets offer worthwhile protection, where they are unnecessary and what can be done about the concerns in between.
My own approach is to get appropriate advice, budget for the protection I need and make it a manageable part of the trip. I would much rather spend my time enjoying somewhere than worrying about whether I should have prepared differently. Once those decisions are made, taking a tablet can become a small daily or weekly habit while the adventure gets most of your attention.
You do not need to plan every day of your gap year or anticipate every possible detour. You need a sensible starting plan, an understanding of when it needs updating and a way to obtain help if something does not suit you. This is general information to help you have that conversation; your individual recommendation should come from a qualified travel health professional who understands your health and intended journey.
Where antimalarials are recommended, take that protection seriously and work through anything that makes following the advice difficult. Then pack the tablets alongside your repellent and get back to the much more enjoyable business of deciding where to go next.
Michael Huxley
Michael Huxley is the founder of Bemused Backpacker, a travel writer, published author, international speaker and former nurse who has spent more than twenty-five years travelling independently through over 150 countries. He helps readers travel with more confidence, safety and perspective.
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52 responses to “Do You Really Need Anti Malarial Medication On Your Gap Year?”
Thanks for that. This article came just at the right time for me as I’m just about to go get all my shots. I was wondering, how hard is it to get good anti-malarials on the road? I’m going to SE Asia but my trip is pretty open ended so I don’t know all the places I’ll be going to yet or how long I could be in a malarial zone. So it makes it hard for the doctor here to prescribe something.
Hi Amanda, I’m glad you found it useful. ๐
Buying anti malarials on the road is very easy across SE Asia, and is a lot cheaper than buying it at home too. Countries such as Singapore, Thailand and Malaysia for example have amazing levels of health care, but some things are different. In Thailand for example you can buy most medication at reputable pharmacies over the counter without a prescription. Just ensure that you are buying from reputable and professional pharmacists.
One thing you SHOULD discuss with your GP or nurse specialist before you go is which antimalarial is right for you and find out if you will suffer any side effects. You don’t want to figure that out when you are out there.
Also be aware that depending on where you go you may not need them at all as much of SE Asia is low risk. Unless you are spending a significant amount of time in the Northern border of Thailand/Myanmar or inland Borneo where the risk of Malaria is high you may get away with needing them. Use the Malaria map from the CDC and try to figure out how long you will be spending in the red zones based on your route.
Good advice. I’ve taken a few different anti-malarials for my travels, each with different side-effects, but however unpleasant I wouldn’t take the risk of forgoing them and contracting malaria. Where photosensitivity is a risk, pack a hat with a wide brim and sunblock, and use it regularly on your face and neck. I took a net with me in Africa and Central America, and at the end of my trips gave it to a family with young children rather than pack it back home.
Great tips, I completely agree. Getting the balance right and choosing the right meds can be tricky, but it isn’t worth taking the risk of contracting malaria if you are travelling in a high risk zone. Thanks for commenting. ๐
Great article! Very informative.. I lived in an area with high risk of Malaria. In the Netherlands I got pills for that and never had any problems although these mosquitoยดs kept feeding themselves with my own blood. I was very happy for the pills as my little Ugandan brother got malaria 3 times while we were sleeping in the same room. Thanks for informing others about the risk and the prevention!
Thank you for the comment I really appreciate it! It’s good that you had the foresight to get the malaria pills beforehand!
I prefer the Deet spray and have never used any of those pills. So far it worked for me.
I take it you’ve stuck to places with low or no risk of malaria then Charles? Preventative measures are perfect in those areas and antimalarials aren’t always necessary. In high risk areas though they are still strongly advised.
I have been to rural areas of Myanmar.
I have been to more places in Cambodia than just Phnom Penh and Siem Reap.
I have been in the south of Laos recently and once in a jungle area in central Laos.
So I have been to some so called high risk places. But in those high risk areas I really use the spray excessively and spray my T-shirt before wearing it and so on. Like this I can reduce the bites to 3 to 5 in one week. And that is a risk I’m willing to take.
Maybe I would take the drugs if I go to Africa one day, as it seems to be much worse there.
Which areas, that you have been, did you use the medication? I’m curious. ๐
Charles I suggest you look at the malaria map on the link above. Much of S.E Asia is low or no risk, (it even varies within certain countries) but there are parts – such as rural areas of Myanmar – that are as high risk as much as parts of Africa are. High risk is high risk, and antimalarials are always advised in those areas. Whether you take them or not is completely up to you, I am not imposing a decision on anyone in any way shape or form I just want to inform people of the risk, but it only takes one single bite from an infected mosquito to contract malaria. Preventative measures help reduce the bites and therefore the risk, but they won’t help if you still get bitten by an infected mosquito.
As for me? Haiti, Belize (due to significant time in the jungle),Nicaragua, Panama, Congo, Rwanda, Ivory Coast, Myanmar… and others. I’ve been to plenty of countries where I assessed the risk wasn’t high enough for me to take them too. It’s all about personal choice based on risk assessment. Just make sure that risk assessment is based on the right info.:) Thanks for commenting and visiting.
I love this site. Thank you so much for this. I went to my GP for the exact same advice and it wasn’t nearly as thorough! Would you mind if I emailed you a couple of extra questions about malaria tablet side effects?
Thank you Alice, I hope you found the article useful? And of course I wouldn’t mind at all, I’m here to help. Just use the contact form on the banner at the top of the page. ๐
Hmm, I might need dumbed down version of the post? Haha
If you have any questions or want me to clarify anything Mark then please feel free to ask or send me an email through the contact form above if you prefer? I’m happy to provide more information or clarification. ๐
We spent 10 months in Southeast Asia and didn’t take any malaria tablets at all – and nothing happened. It was a calculated risk because we had heard that the tablets were really expensive and that the side effects of taking them could be worse than actually having malaria.
That’s partly the point Kelly, you need to research and know what the risk is in the places you are going and act accordingly. The vast majority of SE Asia is low to no risk, especially if you stick to the more popular trails and antimalarials generally aren’t required or advised there with the exception of one or two notable areas such as Laos for example. You have it half right, the side effects are sometimes quite bad in some individuals (not everyone gets all if any of the side effects, everyone reacts differently), and if there is a very low or no risk of malaria then yes the cons outweigh the benefits of taking them. However if you plan on spending any length of time in a high risk area then suddenly the benefits outweigh the cons. Yes the side effects may be bad, but so is potentially dying from a malarial mosquito bite if you don’t get treatment in time. It’s all about research, having the right information from the right sources and risk assessment.
Great article, we are preparing for our 6 week Africa Safari and need to stock up on Malaria meds soon.
Thanks, I’m really glad you found it useful.
Thank you for posting this! I spent a bunch of money on malaria medication that I never even ended up taking. I think doctors prescribe it just to cover their asses. Jules took one (i think it was doxy) and ended up having really weird dreams and just feeling super out of it. Not how you want to feel in a foreign country!
Why did you buy it and not take it? Where you in a high risk area?
I don’t think it is about covering their asses, medical professionals will generally err on the side of caution and prescribe prophylaxis if there is a real risk of malaria.
The key is to know the exact level of risk in the areas you are visiting (there is generally no need for antimalarials in low risk areas), and also to know which prophylaxis works best for you. Antimalarials affect individuals very differently, one person may experience heavy side effects, the next none at all, and that is why it is recommended to take a test run a month or so before you leave.
I’m glad the article was useful for you though. Thanks for the comment. ๐
Great post, itโs nice that you tell people to consider all the variables instead of just nagging them they should get vaccinated โjust in caseโ. Although you missed one of the biggest variables of all, the season when you travel to the country!
I went to India during the dry season and asked a local doctor if I should be worried. He told me that he almost never sees any cases (local or foreign) of malaria during the dry season and that is extremely rare. I only know this for sure in South Western India but I think it should be the same for all tropical countries.
Hi Dan, thanks so much for the comment. You can’t really get vaccinated for malaria, but you are right and that is an excellent point. Wet seasons often do present a higher risk of contracting Malaria simply because the mosquitoes carrying the disease are more active and prevalent in those conditions, but that doesn’t mean that malaria isn’t present at all in dry seasons. Studies by the CDC and others are only in early stages at the moment on this issue, and aren’t fully conclusive as of yet. So I would say that whilst you are right and the risks of contracting malaria are lower during dry seasons, In my personal professional opinion I wouldn’t discount them completely. Thanks so much for the interesting comment though. ๐
I am someone that always seems to suffer nasty side effects from Malaria pills.Even the atovaquone- I can’t take it without milk. When we were traveling in Indonesia we had to start taking malaria pills for our jungle trek in Sumatra and I tried taking them the recommended time in advance but they made me too sick. I found on the second try that if I was able to find milk and take them with that, I didn’t get sick. I seem to attract mosquitos of an epic proportion and despite my bathing in repellent I got bit up pretty good camping in the jungle, so I was glad that I kept taking them. It’s a hard decision, especially when you get side effects. Great article, thanks!
Everyone reacts very differently to prophylaxis, some get really bad symptoms, some get none at all, many fall on a sliding scale somewhere in the middle. I agree that the side effects can be rough for some people, but when you consider the risks of the alternative the decision becomes much easier. Thanks for the comment. ๐
Great informative and in depth article.
This is has already been asked earlier, but I wanted to get some more specifics.
Last year while travelling in India I was taking Atovaquone when in high risk areas, however they were too pricey so am not going to take them again.
Am off to Myanmar, Laos, Cambodia and Vietnam for 3-4 months and have got some leftover Atovaquone which I might start with to last me 2 weeks, then I’ve got some Doxycycline to cover me for the next month, but was wondering on the availability and price of further anti-malarials while out there, specifically in Laos, Cambodia and Vietnam?
Thanks Henry, I’m glad you enjoyed it and hope you found it useful. I try to give out as much information and advice as I can. For specific questions and in depth consultations however I now offer this service here http://bemusedbackpacker.com/services/travel-clinic/ which you may find useful.
I have to agree with Henry – this is one of the most detailed and “usable” guides to avoiding malaria while travelling. Very nicely done sir!
Thank you very much Petra! I’m really happy to be of use. ๐ Thanks for the comment.
Thank you so much for this article! Question, do you recommend how to get this medicine while in South America? Insurance dos not cover it, and it is very costly at over $6 per pill where I am! Thanks!
You’re welcome Amanda. I’m not sure exactly what you are asking, if you are asking if you are able to buy antimalarials in south America, then yes you can. You can buy them in many reputable clinics, pharmacies and hospitals. But I would still advise you to consult with a professional before you leave to ensure you are taking the RIGHT antimalarial for a) the region and b ) you as an individual. Also, south America is a HUGE region, and not everywhere will require antimalarials, so a lot would depend on where you are going on whether you will need them or not.
Nice tips for travellers. Prevention from mosquitoes bites is very important. We need to follow guideline for mosquitoes spread diseases.
We absolutely do.
I found this SO useful, thank you. I’ve been trying to research this for ages but have found all the stuff online to be really contradictory. It’s good to know that you’re a nurse too so all of this is coming from a good, expert source. Thank you!
Thanks Sarah, I’m genuinely happy it helped. Feel free to ask any questions if you still need anything clarifying.
Thanks for this, I was looking for something that would explain all this to me properly in plain English! It’s so confusing to know which information to trust sometimes.
I know what you mean. I’m glad it was helpful. ๐
Perfect! I was so confused and worried about antimalarials, I wasn’t sure what I needed to do for my upcoming trip and my GP wasn’t much help! Could I make an appointment with you to ask a few more questions?
Of course Donna, just fill in the form for the travel clinic in the main menu and I’ll set you up with an appointment. ๐ And don’t worry, not all GPs have specialist knowledge or experience in this area, which is why specialist travel clinics are usually a better bet.
Hiya, I’m just wondering if you know how easy it is to buy malarone (or other brand equivalents of atovaquone and proguanil) in South America? I know this one works for me, but as I won’t be in an at risk area until quite a long way through my trip i’d prefer to get them out there if possible. Thanks!
Hi Kat, Malarone isn’t generally licensed for sale in South America, but you can get Mefloquine (Lariam, Tropicur, generic mefloquina) and doxycycline (doxiciclina, vibramicina), which are effective in preventing malaria in South America and will be less expensive than in the UK. Of course it depends on whether those options are right for you.
Thank you for this, I’ve been trying to get some plain and simple facts about what to do for my own trip and this is the first site I have found to give me just that.
You’re very welcome Craig. ๐
This is an incredibly in-depth article about Malaria medication and I learned a lot from this.
I’m planning a holiday to South East Asia and this article is just what I was looking for. I’ve also heard that Dengue fever is another disease which is carried by mosquitos and can often be more widespread.
Thank you, I’m really glad you found it useful. And absolutely dengue is something you should prepare for, I’ve written a lot on that to just type it into the search bar.
Such an amazing article, thank you. I agree completely that no one likes taking the medication, but it just isn’t worth the risk of not taking it sometimes.
Thanks Ben, you are absolutely right.
Very interesting post, and it is good to hear the other balanced side of it from a professional pov.
Thanks ๐
Such a good, honest and straightforward take on this without all the BS, thanks so much.
Thank you Chloe! Glad you enjoyed it and hope it is useful for you.
I heard anti malarials are a cure for covid is this true?
No.